Methotrexate daily error — GPhC CRA MCQ
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Correct answer: D — Stop methotrexate and arrange urgent medical assessment
Daily methotrexate dosing error can cause serious toxicity and requires urgent assessment. In this vignette, "Stop methotrexate and arrange urgent medical assessment" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.
Reference: BNF; NICE CKS