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Paracetamol liver disease — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentParacetamol liver diseaseGPhC CRA

A patient with stable chronic liver disease asks about occasional paracetamol for headache. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Use within advised dosing and avoid duplicate paracetamol-containing products

Paracetamol may still be used in many patients with liver disease within appropriate limits, but overdose and duplication are important risks. In this vignette, "Use within advised dosing and avoid duplicate paracetamol-containing products" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF