Long-term PPI risk — GPhC CRA MCQ

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EasyGastrointestinal TherapeuticsLong-term PPI riskGPhC CRA

An older patient has taken high-dose omeprazole for years and now has muscle cramps and fatigue. What monitoring is required?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Magnesium concentration and renal function

Long-term PPIs can be associated with hypomagnesaemia and renal adverse effects. In this vignette, "Magnesium concentration and renal function" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF; NICE CKS