Penicillin allergy cellulitis — GPhC CRA MCQ

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EasyInfectionsPenicillin allergy cellulitisGPhC CRA

A patient with cellulitis has a history of immediate penicillin anaphylaxis. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Clarithromycin

A macrolide may be used when penicillin allergy precludes flucloxacillin, subject to local guidance. In this vignette, "Clarithromycin" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF; NICE CKS