Warfarin and tramadol — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateDrug InteractionsWarfarin and tramadolGPhC CRA

A patient stabilised on warfarin is prescribed tramadol for acute back pain. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Increased risk of bleeding

Tramadol can increase bleeding risk with warfarin and has been highlighted in safety communications. In this vignette, "Increased risk of bleeding" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF