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Topiramate pregnancy prevention — GPhC CRA MCQ

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EasyAdverse Drug Reactions and SafetyTopiramate pregnancy preventionGPhC CRA

A woman taking topiramate for migraine says she is trying to conceive. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Refer promptly for prescriber review before further use

Topiramate has pregnancy safety restrictions and requires review in women who may become pregnant. In this vignette, "Refer promptly for prescriber review before further use" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF; MHRA Drug Safety Update