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GLP-1 gastrointestinal effects — GPhC CRA MCQ

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ModeratePatient Counselling and Pharmaceutical CareGLP-1 gastrointestinal effectsGPhC CRA

A patient starts semaglutide and asks about nausea. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Eat smaller meals and seek advice if severe abdominal pain or persistent vomiting occurs

GLP-1 receptor agonists commonly cause gastrointestinal effects but severe symptoms need review. In this vignette, "Eat smaller meals and seek advice if severe abdominal pain or persistent vomiting occurs" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF; NICE CKS; GPhC Standards