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Opioid constipation — GPhC CRA MCQ

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HardGastrointestinal TherapeuticsOpioid constipationGPhC CRA

A patient starting modified-release oxycodone is not prescribed a bowel regimen. What is the most appropriate alternative?

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Correct answer: DMacrogol or stimulant laxative regimen

Opioid-induced constipation should be anticipated and treated proactively. In this vignette, "Macrogol or stimulant laxative regimen" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF; NICE CKS