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Digoxin and amiodarone — GPhC CRA MCQ

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HardDrug InteractionsDigoxin and amiodaroneGPhC CRA

A patient taking digoxin starts amiodarone after cardiology review. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: CIncreased digoxin concentration

Amiodarone can increase digoxin levels, requiring monitoring and dose consideration. In this vignette, "Increased digoxin concentration" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF