Lithium and ibuprofen — GPhC CRA MCQ

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HardCNS TherapeuticsLithium and ibuprofenGPhC CRA

A patient taking lithium asks to buy ibuprofen for dental pain. What is the most important interaction to flag?

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Correct answer: D — Increased risk of lithium toxicity

NSAIDs can increase lithium concentrations and toxicity risk. In this vignette, "Increased risk of lithium toxicity" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: https://www.pharmacyregulation.org/registration-assessment#stage-8-order-82