skip to main content

Sildenafil and GTN — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateDrug InteractionsSildenafil and GTNGPhC CRA

A patient using GTN spray asks to buy sildenafil. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: B — Severe hypotension

Nitrates and PDE5 inhibitors together can cause dangerous hypotension. In this vignette, "Severe hypotension" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF