Methotrexate safety — GPhC CRA MCQ
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Correct answer: E — Full blood count, liver function tests and renal function
Methotrexate can cause myelosuppression, hepatotoxicity and toxicity in renal impairment. In this vignette, "Full blood count, liver function tests and renal function" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.
Reference: BNF; NICE CKS