Theophylline concentration — GPhC CRA MCQ

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ModerateRespiratory TherapeuticsTheophylline concentrationGPhC CRA

A patient on modified-release theophylline has had a dose increase. The GP asks what safety monitoring is relevant. What monitoring is required?

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Correct answer: B — Serum theophylline concentration

Theophylline has a narrow therapeutic index and plasma levels are used to guide safe dosing. In this vignette, "Serum theophylline concentration" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: https://www.pharmacyregulation.org/registration-assessment#stage-8-order-81