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Montelukast neuropsychiatric reaction — GPhC CRA MCQ

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EasyAdverse Drug Reactions and SafetyMontelukast neuropsychiatric reactionGPhC CRA

A parent reports new aggression and nightmares after their child started montelukast. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Advise prompt prescriber review and consider reporting the suspected reaction

Neuropsychiatric reactions are recognised with montelukast and require review. In this vignette, "Advise prompt prescriber review and consider reporting the suspected reaction" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF; MHRA Drug Safety Update