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Metformin AKI — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentMetformin AKIGPhC CRA

A patient taking metformin has acute kidney injury after dehydration and is discharged with eGFR 25. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Withhold metformin and refer for prescriber review

Metformin is unsuitable in significant renal impairment or acute kidney injury because lactic acidosis risk increases. In this vignette, "Withhold metformin and refer for prescriber review" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF