Antibiotic in COPD exacerbation — GPhC CRA MCQ

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ModerateRespiratory TherapeuticsAntibiotic in COPD exacerbationGPhC CRA

A patient with COPD has increased sputum purulence and breathlessness. They have no penicillin allergy and no recent antibiotics. What is the most appropriate alternative?

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Correct answer: B — Amoxicillin

Antibiotics may be appropriate in COPD exacerbations with increased sputum purulence, selected using local guidance. In this vignette, "Amoxicillin" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF; NICE CKS