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Lithium and thiazide — GPhC CRA MCQ

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ModerateDrug InteractionsLithium and thiazideGPhC CRA

A patient taking lithium is prescribed bendroflumethiazide for hypertension. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Increased risk of lithium toxicity

Thiazides can raise lithium concentrations and toxicity risk. In this vignette, "Increased risk of lithium toxicity" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF