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Nitrofurantoin low eGFR — GPhC CRA MCQ

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EasyRenal and Hepatic ImpairmentNitrofurantoin low eGFRGPhC CRA

A patient with eGFR 24 mL/min/1.73 m2 is prescribed nitrofurantoin for cystitis. What is the most appropriate action?

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Correct answer: D — Contact the prescriber because nitrofurantoin is unsuitable at this renal function

Nitrofurantoin efficacy falls and toxicity risk increases in significant renal impairment. In this vignette, "Contact the prescriber because nitrofurantoin is unsuitable at this renal function" is the safest single best answer. The other options are less appropriate because they miss the key clinical risk, conflict with UK medicines guidance, or delay needed review.

Reference: BNF