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Macrogol in renal disease — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentMacrogol in renal diseaseGPhC CRA

A 76-year-old man with chronic kidney disease asks for constipation treatment. He has no bowel obstruction symptoms and takes ramipril. He asks whether sodium phosphate enemas are a good first choice. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Consider macrogol and assess for red flags and medicine causes

Macrogol is commonly used for constipation and is generally safer than phosphate or magnesium preparations in renal impairment. Sodium phosphate preparations can cause electrolyte disturbance and renal complications. Red flags and constipating medicines should be assessed before supply.

Reference: BNF; NICE CKS