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Enoxaparin renal impairment — GPhC CRA MCQ

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HardRenal and Hepatic ImpairmentEnoxaparin renal impairmentGPhC CRA

A hospital discharge prescription includes enoxaparin for venous thromboembolism treatment in a patient with creatinine clearance 24 mL/min. The dose appears to be the standard twice-daily regimen. No anti-Xa plan is documented. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Query the dose because low molecular weight heparin accumulates in renal impairment

Low molecular weight heparins are partly renally cleared and can accumulate in significant renal impairment. Treatment dosing may require adjustment, monitoring or an alternative anticoagulant depending on local policy. The discharge team should be contacted before supply.

Reference: BNF