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Penicillin allergy and sore throat — GPhC CRA MCQ

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EasyInfectionsPenicillin allergy and sore throatGPhC CRA

A 22-year-old woman with a documented immediate penicillin allergy is prescribed phenoxymethylpenicillin for acute tonsillitis. She previously developed wheeze and facial swelling after amoxicillin. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: C — Clarify allergy and contact the prescriber for a non-penicillin option

A history of wheeze and facial swelling suggests a possible IgE-mediated penicillin allergy. Phenoxymethylpenicillin should not be supplied without prescriber review in this context. A suitable non-penicillin antibiotic may be needed depending on the indication and local guidance.

Reference: NICE CKS; BNF