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Carbimazole blood disorder — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsCarbimazole blood disorderGPhC CRA

A 33-year-old woman taking carbimazole for Graves' disease asks to buy lozenges for a sore throat and fever. She started treatment three weeks ago. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Advise urgent medical assessment and full blood count

Carbimazole can rarely cause agranulocytosis, particularly early in treatment. Fever and sore throat should be treated as warning symptoms requiring urgent assessment and blood count. Symptomatic treatment alone could delay recognition of a serious adverse reaction.

Reference: BNF; NICE CKS