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Hypertension step-up therapy — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsHypertension step-up therapyGPhC CRA

A 62-year-old man takes amlodipine 10 mg once daily for hypertension. His home blood pressure readings remain around 152/92 mmHg. His eGFR is 78 mL/min/1.73 m2 and potassium is 4.4 mmol/L. What is the most appropriate alternative?

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Correct answer: D — Add ramipril

For hypertension not controlled on a calcium-channel blocker, adding an ACE inhibitor or ARB is a common next step if renal function and potassium permit. Ramipril is therefore appropriate in this patient. Spironolactone is usually considered later for resistant hypertension and needs careful potassium assessment.

Reference: https://www.pharmacyregulation.org/students-and-trainees/pharmacist-education-and-training/registration-assessment