Hypertension first-line treatment — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsHypertension first-line treatmentGPhC CRA

A 43-year-old man of Black African family origin attends a GP practice after ambulatory blood pressure monitoring. His daytime average is 158/98 mmHg. He has no diabetes, no target organ damage and no regular medicines. What is the most appropriate alternative?

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Correct answer: C — Amlodipine

For adults of Black African or African-Caribbean family origin without type 2 diabetes, a calcium-channel blocker is preferred as first-line treatment for hypertension. Amlodipine is an appropriate once-daily dihydropyridine calcium-channel blocker. ACE inhibitors or ARBs may be used in other groups, but are less appropriate as initial monotherapy in this scenario.

Reference: NICE CKS; BNF