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Mesalazine monitoring — GPhC CRA MCQ

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HardGastro-intestinal TherapeuticsMesalazine monitoringGPhC CRA

A 40-year-old man with ulcerative colitis starts oral mesalazine. The GP asks the pharmacist which baseline and follow-up checks should be arranged. What monitoring is required?

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Correct answer: C — Renal function monitoring

Mesalazine can rarely cause renal impairment, including interstitial nephritis. Renal function should be checked before treatment and monitored periodically during therapy. Patients should report unexplained bruising, bleeding, sore throat or worsening symptoms where relevant.

Reference: https://www.pharmacyregulation.org/registration-assessment#stage-8-order-79