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Triptan cardiovascular caution — GPhC CRA MCQ

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ModerateCNS TherapeuticsTriptan cardiovascular cautionGPhC CRA

A 57-year-old man asks to buy sumatriptan for severe unilateral headaches with nausea. His record shows previous myocardial infarction and current isosorbide mononitrate. He has not used a triptan before. What is the most appropriate action?

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Correct answer: C — Do not supply and refer for medical assessment

Triptans are contraindicated or unsuitable in patients with significant ischaemic heart disease because of vasoconstrictive effects. The patient's nitrate therapy and previous myocardial infarction make over-the-counter supply inappropriate. New or severe headache patterns also require careful assessment.

Reference: https://www.pharmacyregulation.org/registration-assessment#stage-8-order-77