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Antipsychotic extrapyramidal effects — GPhC CRA MCQ

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HardAdverse Drug Reactions and Drug SafetyAntipsychotic extrapyramidal effectsGPhC CRA

A 28-year-old man started haloperidol five days ago. He presents with painful neck muscle spasm and abnormal upward eye deviation. He is frightened but alert. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Urgent treatment for acute dystonia such as procyclidine according to local protocol

Acute dystonia is a recognised extrapyramidal adverse effect of antipsychotics, particularly early in treatment. It can be distressing and requires prompt treatment, commonly with an antimuscarinic such as procyclidine. The antipsychotic regimen should be reviewed by the prescriber.

Reference: BNF; NICE CKS