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ACE inhibitor angioedema — GPhC CRA MCQ

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EasyAdverse Drug Reactions and Drug SafetyACE inhibitor angioedemaGPhC CRA

A 55-year-old man taking lisinopril for six months presents with swollen lips and tongue. He has no rash. He is speaking but says his throat feels tight. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: A — Arrange emergency medical help for suspected angioedema

ACE inhibitors can cause angioedema at any time during treatment. Tongue or throat symptoms may threaten the airway and require emergency assessment. The ACE inhibitor should not be continued unless a prescriber has reviewed the event, and alternative treatment will be needed.

Reference: BNF; NICE CKS