NSAID triple whammy — GPhC CRA MCQ
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Correct answer: C — Ibuprofen with ACE inhibitor and diuretic increases acute kidney injury risk
NSAIDs combined with ACE inhibitors or ARBs and diuretics increase the risk of acute kidney injury. Existing chronic kidney disease increases the concern. The patient should be advised against self-treatment with ibuprofen and offered safer options or referral.
Reference: BNF; NICE CKS