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Hepatic impairment paracetamol risk — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentHepatic impairment paracetamol riskGPhC CRA

A 58-year-old man with cirrhosis asks to buy paracetamol for dental pain. He drinks alcohol daily and has poor nutritional intake. He is not jaundiced today. What is the most appropriate action?

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Correct answer: A — Refer for pharmacist assessment and avoid routine maximum-dose self-treatment

Paracetamol may still be used in some liver disease contexts, but dose and safety require careful assessment. Chronic alcohol use and malnutrition increase toxicity risk. The pharmacist should assess current medicines, liver status and need for dental or medical referral before advising.

Reference: BNF