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Drug-induced hyponatraemia — GPhC CRA MCQ

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ModerateAdverse Drug Reactions and Drug SafetyDrug-induced hyponatraemiaGPhC CRA

An 86-year-old woman starts bendroflumethiazide for hypertension. Two weeks later she is confused and has had a fall. Her daughter says fluid intake has been normal. What monitoring is required?

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Correct answer: B — Serum sodium, renal function and clinical assessment

Thiazide diuretics can cause hyponatraemia, particularly in older adults. New confusion and falls soon after initiation should prompt assessment of sodium and renal function. The medicine regimen and falls risk should be reviewed urgently.

Reference: BNF; NICE CKS