skip to main content

NSAID gastroprotection — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateGastro-intestinal TherapeuticsNSAID gastroprotectionGPhC CRA

A 74-year-old woman with osteoarthritis is prescribed naproxen 500 mg twice daily for four weeks. She has a previous peptic ulcer and takes low-dose aspirin. No gastroprotection is prescribed. What is the most appropriate alternative?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Review NSAID need and add PPI if continued

Older age, previous ulcer disease and antiplatelet therapy increase NSAID-related gastrointestinal bleeding risk. A PPI is commonly used for gastroprotection when an NSAID is necessary, and the need for naproxen should be reviewed. Taking naproxen on an empty stomach does not reduce ulcer risk.

Reference: https://www.pharmacyregulation.org/students-and-trainees/pharmacist-education-and-training/registration-assessment