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Gliclazide hypoglycaemia — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsGliclazide hypoglycaemiaGPhC CRA

A 72-year-old man taking gliclazide 80 mg twice daily reports several episodes of sweating and confusion before lunch. He has recently lost weight and is eating smaller meals. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: CRefer for diabetes medication review because hypoglycaemia is likely

Sulfonylureas such as gliclazide can cause hypoglycaemia, particularly with reduced food intake, weight loss or renal impairment. Recurrent symptoms require review of dose and overall diabetes management. The patient should receive advice on treating hypoglycaemia safely.

Reference: BNF; NICE CKS