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Liver disease statin assessment — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentLiver disease statin assessmentGPhC CRA

A 60-year-old man with non-alcoholic fatty liver disease is prescribed atorvastatin 20 mg daily for primary prevention. His ALT is mildly elevated but stable. He is worried that statins are banned in liver disease. What would you advise the patient?

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Correct answer: C — Mild stable transaminase elevation does not automatically prevent statin use

Statins are avoided in active liver disease or unexplained persistent significant transaminase elevations, but mild stable abnormalities may not preclude treatment. Baseline and follow-up liver function monitoring are used to support safe prescribing. The patient should report severe muscle symptoms or signs of liver injury.

Reference: BNF; NICE CKS