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Valproate pregnancy risk — GPhC CRA MCQ

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HardCNS TherapeuticsValproate pregnancy riskGPhC CRA

A 25-year-old woman taking sodium valproate for epilepsy asks for emergency contraception after unprotected sex. Her record shows no recent specialist review. She says she may want a pregnancy next year. What is the most appropriate action?

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Correct answer: C — Supply or refer for emergency contraception and advise urgent specialist review of valproate treatment

Valproate is highly teratogenic and is subject to strict pregnancy prevention requirements. Emergency contraception should be addressed promptly, while the ongoing valproate regimen needs specialist review. Abrupt discontinuation can trigger seizures and should not be advised without specialist input.

Reference: BNF; MHRA Drug Safety Update