A 59-year-old man of Black African family origin has type 2 diabetes, no albuminuria, eGFR 70 mL/min/1.73 m² and confirmed clinic BP 152/96 mmHg.

Question

A 59-year-old man of Black African family origin has type 2 diabetes, no albuminuria, eGFR 70 mL/min/1.73 m² and confirmed clinic BP 152/96 mmHg. Which step-1 antihypertensive choice best reflects NICE NG136?

Accepted Answer

Losartan, applying the diabetes RAS-blocker rule and ARB preference for family origin

Answer

Ramipril, applying the diabetes RAS-blocker rule but disregarding the ARB preference

Answer

Indapamide, treating absence of albuminuria as exclusion of all RAS blockade

Answer

Doxazosin, reserving first-line classes because diabetes is present

Answer

Amlodipine, applying the age-and-family-origin rule without the diabetes exception

Hypertension with diabetes — GPhC CRA MCQ

A 59-year-old man of Black African family origin has type 2 diabetes, no albuminuria, eGFR 70 mL/min/1.73 m² and confirmed clinic BP 152/96 mmHg. Which step-1 antihypertensive choice best reflects NICE NG136?