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DOAC renal monitoring — GPhC CRA MCQ

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HardRenal and Hepatic ImpairmentDOAC renal monitoringGPhC CRA

A patient with atrial fibrillation is prescribed rivaroxaban 20 mg once daily and takes all medicines at bedtime without food. Which counselling is essential?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Take each 20 mg dose with a meal for reliable absorption

Rivaroxaban 15 mg and 20 mg tablets must be taken with food because bioavailability is lower in the fasted state. The tablet may be crushed when needed, but the dose still needs food and should follow immediately after administration.

Reference: BNF: rivaroxaban: https://bnf.nice.org.uk/drugs/rivaroxaban/