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Montelukast neuropsychiatric effects — GPhC CRA MCQ

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ModerateRespiratory TherapeuticsMontelukast neuropsychiatric effectsGPhC CRA

A mother asks about her 10-year-old son who started montelukast for asthma two weeks ago. He has become unusually anxious and is having nightmares. His asthma symptoms have not worsened. What is the most appropriate action?

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Correct answer: B — Advise prompt prescriber review because neuropsychiatric effects are possible

Montelukast has recognised neuropsychiatric adverse effects, including sleep disturbance, mood change and anxiety. New symptoms after initiation should prompt timely review of the risk-benefit balance. The family should not alter asthma medicines without a plan from the prescriber.

Reference: BNF; MHRA Drug Safety Update