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Isotretinoin monitoring — GPhC CRA MCQ

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ModerateAdverse Drug Reactions and Drug SafetyIsotretinoin monitoringGPhC CRA

A woman taking isotretinoin for severe acne asks whether monitoring can stop because her skin has improved. She has one month of treatment remaining and is of childbearing potential. What monitoring is required?

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Correct answer: C — Pregnancy testing and pregnancy prevention checks according to the specialist programme

Isotretinoin is highly teratogenic and is subject to strict pregnancy prevention requirements. Monitoring and documentation should continue as directed by the specialist programme while treatment is ongoing. The patient should not change contraception or monitoring arrangements without dermatology advice.

Reference: BNF; MHRA Drug Safety Update