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GLP-1 agonist counselling — GPhC CRA MCQ

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ModerateEndocrine TherapeuticsGLP-1 agonist counsellingGPhC CRA

A woman starting semaglutide injection for type 2 diabetes asks what adverse effects she should expect. She has no personal history of pancreatitis. She is also taking metformin. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: B — Nausea and gastrointestinal symptoms are common, and severe persistent abdominal pain needs urgent advice

GLP-1 receptor agonists commonly cause nausea, vomiting, diarrhoea or constipation, especially during dose escalation. Severe persistent abdominal pain may suggest pancreatitis and requires urgent assessment. Metformin is often continued unless tolerability or renal function requires review.

Reference: BNF; NICE CKS