skip to main content

Methotrexate monitoring — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

HardPatient Counselling and Pharmaceutical CareMethotrexate monitoringGPhC CRA

A new rheumatoid-arthritis prescription states methotrexate 15 mg once weekly. Which dispensing arrangement best reduces fatal weekly-dosing errors?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: E — Supply only 2.5 mg tablets with one clearly specified weekly day

For low-dose weekly methotrexate, one tablet strength—normally 2.5 mg—and one explicit weekly dosing day reduce selection and frequency errors. The prescription, label, PMR and counselling should agree; unusual use of 10 mg tablets needs a clear clinical reason and robust safeguards.

Reference: BNF: methotrexate: https://bnf.nice.org.uk/drugs/methotrexate/