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ACE inhibitor angioedema — GPhC CRA MCQ

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ModerateAdverse Drug Reactions and Drug SafetyACE inhibitor angioedemaGPhC CRA

A woman started lisinopril two weeks ago and now has lip and tongue swelling with throat tightness. What is the most appropriate action?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: E — Call emergency services for suspected ACE inhibitor angioedema

This scenario assesses ACE inhibitor angioedema in a UK pharmacy practice context. Airway swelling is an emergency and ACE inhibitors can cause angioedema without rash. The best answer is Call emergency services for suspected ACE inhibitor angioedema because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF; MHRA