skip to main content

Colchicine clarithromycin CKD — GPhC CRA MCQ

Instant feedback + full explanation. One question, done properly.

ModerateMusculoskeletal TherapeuticsColchicine clarithromycin CKDGPhC CRA

A man with eGFR 24 is prescribed colchicine for gout while taking clarithromycin. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Colchicine toxicity risk is increased

This scenario assesses Colchicine clarithromycin CKD in a UK pharmacy practice context. Colchicine has a narrow therapeutic index and clarithromycin plus renal impairment markedly increases toxicity risk. The best answer is Colchicine toxicity risk is increased because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF