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Topiramate pregnancy prevention — GPhC CRA MCQ

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ModerateAdverse Drug Reactions and Drug SafetyTopiramate pregnancy preventionGPhC CRA

A woman taking topiramate for migraine is not using contraception and may try for pregnancy. What is the most appropriate action?

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Correct answer: C — Clarify pregnancy-prevention and prescriber review before routine supply

This scenario assesses Topiramate pregnancy prevention in a UK pharmacy practice context. Topiramate has pregnancy-prevention restrictions because of fetal risk. The best answer is Clarify pregnancy-prevention and prescriber review before routine supply because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: MHRA Drug Safety Update; BNF