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Amiodarone and warfarin — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsAmiodarone and warfarinGPhC CRA

A man stable on warfarin is started on amiodarone after a cardiology admission. His next INR appointment is six weeks away. What is the most important interaction to flag?

Educational content. Not a substitute for clinical judgement or local policy.

Reveal the answer and explanation

Correct answer: D — Increased warfarin effect and bleeding risk

This scenario assesses Amiodarone and warfarin in a UK pharmacy practice context. Amiodarone inhibits warfarin metabolism and can increase INR, requiring earlier anticoagulation review. The best answer is Increased warfarin effect and bleeding risk because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF