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Apixaban dose assessment — GPhC CRA MCQ

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ModerateCardiovascular TherapeuticsApixaban dose assessmentGPhC CRA

A GP asks about apixaban for a 79-year-old woman with AF who weighs 53 kg and has serum creatinine 141 micromol/L. What monitoring is required?

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Correct answer: B — Age, weight, renal function and bleeding risk

This scenario assesses Apixaban dose assessment in a UK pharmacy practice context. Apixaban dosing and suitability require assessment of renal function, age and body weight, alongside bleeding risk and interacting medicines. The best answer is Age, weight, renal function and bleeding risk because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF; NICE CKS