Lithium ramipril — GPhC CRA MCQ
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Correct answer: D — Increased lithium concentration
This scenario assesses Lithium ramipril in a UK pharmacy practice context. ACE inhibitors can increase lithium concentrations by altering renal handling. The best answer is Increased lithium concentration because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.
Reference: BNF