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Methotrexate weekly — GPhC CRA MCQ

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EasyMusculoskeletal TherapeuticsMethotrexate weeklyGPhC CRA

A woman newly prescribed methotrexate 15 mg weekly asks if one tablet daily would be easier. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Take methotrexate once weekly on the chosen day

This scenario assesses Methotrexate weekly in a UK pharmacy practice context. Daily methotrexate dosing errors in inflammatory disease can be fatal. The best answer is Take methotrexate once weekly on the chosen day because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF; MEP