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Metformin AKI — GPhC CRA MCQ

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ModerateRenal and Hepatic ImpairmentMetformin AKIGPhC CRA

A patient discharged after dehydration-related AKI asks for metformin while renal function is due to be rechecked. What is the most appropriate action?

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Correct answer: D — Withhold supply pending renal review and prescriber advice

This scenario assesses Metformin AKI in a UK pharmacy practice context. Metformin should be withheld during acute kidney injury because of lactic acidosis risk. The best answer is Withhold supply pending renal review and prescriber advice because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF; NICE CKS