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SGLT2 sick-day advice — GPhC CRA MCQ

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EasyEndocrine TherapeuticsSGLT2 sick-day adviceGPhC CRA

A woman taking empagliflozin has vomiting and poor oral intake but blood glucose is 9 mmol/L. What would you advise the patient?

Educational content. Not a substitute for clinical judgement or local policy.

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Correct answer: D — Temporarily stop empagliflozin and seek advice about ketones

This scenario assesses SGLT2 sick-day advice in a UK pharmacy practice context. SGLT2 inhibitors can cause ketoacidosis during acute illness even with near-normal glucose. The best answer is Temporarily stop empagliflozin and seek advice about ketones because it addresses the principal clinical, legal or safety issue before routine supply. The other options are less appropriate because they either miss the key risk, delay necessary review, or would not meet expected BNF, NICE, MEP, MHRA or GPhC practice standards.

Reference: BNF; MHRA Drug Safety Update